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What is Modvigil 200 ?

Modalert 200Mg (Modvigil 200 Mg) Tablet is a medicine which is utilized for reducing extreme sleepiness in patients with sleep disorders like narcolepsy. Problematic sleeping complications such as obstructive sleep apnea where the breathing process is seized for a while during sleep is also treated by this drug. It can be generally used for people who feel sleepy during unusual hours due to unpredictable lifestyle. It is also known for its cognitive enhancing abilities. Though it should not be used to keep a person forcefully awake who does not have any sleep disorder. It possibly acts like a dopamine reuptake inhibitor.

This drug is orally administered and should not be overdosed. Side effects of Modalert 200Mg Tablet may give rise to headache, dizziness, nausea, nervousness etc. If used for a long time this drug can affect sleeping habits, and difficulty in getting enough sleep may be experienced. Heart pounding, excessive sweating, agitation, hallucination and similar symptoms should be reported to the doctor at once.

This product has a tendency of interacting with birth control pills and may reduce the efficacy of such medicines which could result in pregnancy. Certain medicines like axitinib, bosutinib, ombitasvir may be affected by Modvigil 200 Mg Tablet, hence doctor’s consultation is necessary in such cases.

Information given here is based on the salt and content of the medicine. Effect and uses of medicine may vary from person to person. It is advicable to consult a Psychiatrist before using this medicine.

PROVIGIL is indicated to improve wakefulness in adult patients with excessive sleepiness associated with narcolepsy, obstructive sleep apnea (OSA), or shift work disorder (SWD).

The recommended dosage of Modvigil 200 Mg for patients with narcolepsy or OSA is 200 mg taken orally once a day as a single dose in the morning.

Doses up to 400 mg/day, given as a single dose, have been well tolerated, but there is no consistent evidence that this dose confers additional benefit beyond that of the 200 mg/day dose.

The Mechanism Of Modafinil Is Unknown But It Appears To Exert Its Stimulant Effects By Reducing GABA-Mediated Neurotransmission. Absorption: Well Absorbed From The GI Tract (Oral); Peak Plasma Concentrations After 2-4 Hr. Distribution: Protein-Binding: Approx 60% (Mainly To Albumin). Metabolism: Hepatic; Partially By CYP3A4 And CYP3A5 Isoenzymes. 2 Major Metabolites: Acid Modafinil And Modafinil Sulfone (Both Inactive). Excretion: Mainly Via Urine (<10% Of The Dose Eliminated Unchanged). Elimination Half-Life: 15 Hr (After Multiple Doses).

Precautions

Modafinil can decrease or increase the activity of enzymes in the liver that metabolize (eliminate) other drugs. This can result in decreased levels of some drugs that reduce their effectiveness and increased levels of other drugs that leads to their toxicity. Modafinil treatment should be carefully monitored if taken with any of these drugs. Drugs which may have reduced effectiveness if taken with modafinil include cyclosporine (Sandimmune), theophylline, and hormonal contraceptives such as progestin-only or estrogen and progesterone containing drugs (for example, Micronor, Ortho-Novum 1/50). Alternative hormonal contraceptives or an additional non-drug form of contraception should be considered during treatment with modafinil, and treatment should continue for one month after modafinil therapy ends (since the effects of modafinil on contraceptive hormones may continue for several weeks). The effects of modafinil on hormonal contraceptives occurs if the hormones are taken by mouth, patch, or implant.

Drugs that may show increased effects or toxicity if taken with modafinil include warfarin (Coumadin), diazepam (Valium), propranolol (Inderal), imipramine (Tofranil), desipramine (Norpramin), phenytoin (Dilantin) and mephenytoin (Mesantoin).

Some other drugs that may increase the effectiveness and/or toxicity of modafinil. These drugs include carbamazepine (Tegretol), phenobarbital, and rifampin (Rifadin).

Other drugs, such as ketoconazole (Nizoral) and itraconazole (Sporanox) may reduce the effectiveness of modafinil. Methylphenidate may delay the action of modafinil.

The effect of alcohol on modafinil has not been adequately evaluated. Alcohol probably should be avoided while taking modafinil.

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